Childhood cognitive development in 22q11.2 deletion syndrome: Case–control study

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Cognitive development in children with 22q11.2 deletion syndrome.

BACKGROUND People with 22q11.2 deletion syndrome (velo-cardio-facial syndrome) have a 30-fold risk of developing schizophrenia. In the general population the schizophrenia phenotype includes a cognitive deficit and a decline in academic performance preceding the first episode of psychosis in a subgroup of patients. Findings of cross-sectional studies suggest that cognitive abilities may decline...

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The development of cognitive control in children with chromosome 22q11.2 deletion syndrome

Chromosome 22q11.2 Deletion Syndrome (22q11.2DS) is caused by the most common human microdeletion, and it is associated with cognitive impairments across many domains. While impairments in cognitive control have been described in children with 22q11.2DS, the nature and development of these impairments are not clear. Children with 22q11.2DS and typically developing children (TD) were tested on f...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2017

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.bp.116.195651